Pseudomonas aeruginosa PAO1, PA2228

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2228
Name
Replicon chromosome
Genomic location 2449554 - 2450765 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250918.1
GI 15597424
Affymetrix PA2228_at
Entrez 879512
GenBank AAG05616.1
INSDC AAG05616.1
NCBI Locus Tag PA2228
protein_id(GenBank) gb|AAG05616.1|AE004649_7|gnl|PseudoCAP|PA2228
TIGR NTL03PA02228
UniParc UPI00000C561A
UniProtKB Acc Q9I1P1
UniProtKB ID Q9I1P1_PSEAE
UniRef100 UniRef100_Q9I1P1
UniRef50 UniRef50_A6UYI4
UniRef90 UniRef90_W0Z3B7

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) -0.17
Kyte-Doolittle Hydrophobicity Value 0.007
Molecular Weight (kDa) 44.2
Isoelectric Point (pI) 6.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 194 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005074 (424 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2228

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the 6-aminohexanoate-dimer hydrolase from Pseudomonas sp. NK87.
Kanagawa K, Oishi M, Negoro S, Urabe I, Okada H
J Gen Microbiol 1993 Apr;139(4):787-95
PubMed ID: 8515236