Pseudomonas aeruginosa PAO1, PA2678

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2678
Name
Replicon chromosome
Genomic location 3024705 - 3025508 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251368.1
GI 15597874
Affymetrix PA2678_at
DNASU PaCD00007155
Entrez 882387
GenBank AAG06066.1
INSDC AAG06066.1
NCBI Locus Tag PA2678
protein_id(GenBank) gb|AAG06066.1|AE004695_19|gnl|PseudoCAP|PA2678
TIGR NTL03PA02678
UniParc UPI00000C57A6
UniProtKB Acc Q9I0G0
UniProtKB ID Q9I0G0_PSEAE
UniRef100 UniRef100_Q9I0G0
UniRef50 UniRef50_Q02NH0
UniRef90 UniRef90_Q02NH0

Product

Feature Type CDS
Coding Frame 1
Product Name
probable permease of ABC-2 transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.86
Kyte-Doolittle Hydrophobicity Value 1.079
Molecular Weight (kDa) 29.7
Isoelectric Point (pI) 9.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 315 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002879 (742 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2678

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295