Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA5384
|
Name |
hocS
|
Replicon | chromosome |
Genomic location | 6062352 - 6063347 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 8 transposon mutants in orthologs |
Comment | Deletion of hocS results in an inability of P. aeruginosa to grow on acetylcarnitine or butyrylcarnitine as sole sources of carbon or nitrogen. Purified HocS hydrolyzes the L-isoforms of acetyl- and butyrylcarnitine. |
RefSeq | NP_254071.1 |
GI | 15600577 |
Affymetrix | PA5384_at |
Entrez | 881643 |
GenBank | AAG08769.1 |
INSDC | AAG08769.1 |
NCBI Locus Tag | PA5384 |
protein_id(GenBank) | gb|AAG08769.1|AE004951_3|gnl|PseudoCAP|PA5384 |
TIGR | NTL03PA05385 |
UniParc | UPI00000C5FD5 |
UniProtKB Acc | Q9HTI0 |
UniProtKB ID | Q9HTI0_PSEAE |
UniRef100 | UniRef100_S0HX90 |
UniRef50 | UniRef50_A6VEJ6 |
UniRef90 | UniRef90_A6VEJ6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
HocS
|
Synonyms |
hydrolysis of O-acylcarnitine, short chain |
Evidence for Translation | |
Charge (pH 7) | -10.07 |
Kyte-Doolittle Hydrophobicity Value | 0.006 |
Molecular Weight (kDa) | 34.9 |
Isoelectric Point (pI) | 5.04 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 347 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001165 (2285 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA5384
Search term: hocS
Search term: HocS
|
Ensembl
110, assembly
GRCh38.p14
|
lipase E, hormone sensitive type [Source:HGNC Symbol;Acc:HGNC:6621]
E-value:
5.5e-15
Percent Identity:
37.1
|
Characterization of Pseudomonas aeruginosa growth on O-acylcarnitines and identification of a short-chain acylcarnitine hydrolase.
Meadows JA, Wargo MJ
Appl Environ Microbiol 2013 Jun;79(11):3355-63
PubMed ID: 23524670
|