Pseudomonas aeruginosa PAO1, PA0001 (dnaA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0001
|
| Name |
dnaA
|
| Replicon | chromosome |
| Genomic location | 483 - 2027 (+ strand) |
Cross-References
| RefSeq | NP_064721.1 |
| GI | 15595199 |
| Affymetrix | PA0001_dnaA_at |
| Entrez | 878417 |
| GenBank | AAG03391.1 |
| INSDC | AAG03391.1 |
| NCBI Locus Tag | PA0001 |
| protein_id(GenBank) | gb|AAG03391.1|AE004440_1|gnl|PseudoCAP|PA0001 |
| TIGR | NTL03PA00002 |
| UniParc | UPI0000129539 |
| UniProtKB Acc | Q9I7C5 |
| UniProtKB ID | DNAA_PSEAE |
| UniRef100 | UniRef100_B7V0N6 |
| UniRef50 | UniRef50_P29440 |
| UniRef90 | UniRef90_B7V0N6 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
chromosomal replication initiator protein DnaA
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | 6.33 |
| Kyte-Doolittle Hydrophobicity Value | -0.286 |
| Molecular Weight (kDa) | 57.7 |
| Isoelectric Point (pI) | 8.88 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000001 (554 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0001
Search term: dnaA
Search term: chromosomal replication initiator protein DnaA
|
Human Homologs
References
|
The nucleotide sequence of the dnaA gene and the first part of the dnaN gene of Escherichia coli K-12.
Hansen EB, Hansen FG, von Meyenburg K
Nucleic Acids Res 1982 Nov 25;10(22):7373-85
PubMed ID: 6296774
|
|
Structural analysis of the dnaA and dnaN genes of Escherichia coli.
Ohmori H, Kimura M, Nagata T, Sakakibara Y
Gene 1984 May;28(2):159-70
PubMed ID: 6234204
|
|
The E. coli dnaA initiation protein: a protein for all seasons.
Georgopoulos C
Trends Genet 1989 Oct;5(10):319-21
PubMed ID: 2558436
|
|
Pseudomonas chromosomal replication origins: a bacterial class distinct from Escherichia coli-type origins.
Yee TW, Smith DW
Proc Natl Acad Sci U S A 1990 Feb;87(4):1278-82
PubMed ID: 2106132
|