Pseudomonas aeruginosa UCBPP-PA14, PA14_54410 (mucB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_54410
Name
mucB
Replicon chromosome
Genomic location 4824497 - 4825447 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_792520.1
GI 116048680
Entrez 4385215
INSDC ABJ09916.1
NCBI Locus Tag PA14_54410
UniParc UPI00003964CC
UniProtKB Acc Q02HR6
UniProtKB ID Q02HR6_PSEAB
UniRef100 UniRef100_Q02HR6
UniRef50 UniRef50_P38108
UniRef90 UniRef90_P38108

Product

Feature Type CDS
Coding Frame 1
Product Name
negative regulator for alginate biosynthesis MucB
Synonyms
Evidence for Translation
Charge (pH 7) -2.88
Kyte-Doolittle Hydrophobicity Value -0.238
Molecular Weight (kDa) 34.6
Isoelectric Point (pI) 6.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6IN9 MEMBRANE PROTEIN 10/24/18 Crystal structure of MucB in complex with MucA(peri) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.801 X-RAY DIFFRACTION 99.3
6JAU PROTEIN BINDING 01/25/19 The complex structure of Pseudomonas aeruginosa MucA/MucB. Pseudomonas aeruginosa (strain PAO1) 1.905 X-RAY DIFFRACTION 99.3
6IN8 MEMBRANE PROTEIN 10/24/18 Crystal structure of MucB Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 99.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 110 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000738 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_54410
Search term: mucB

Human Homologs

References

No references are associated with this feature.