Pseudomonas aeruginosa PAO1, PA0420 (bioA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0420
Name
bioA
Replicon chromosome
Genomic location 466833 - 468236 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249111.1
GI 15595617
Affymetrix PA0420_bioA_at
Entrez 878017
GenBank AAG03809.1
INSDC AAG03809.1
NCBI Locus Tag PA0420
protein_id(GenBank) gb|AAG03809.1|AE004479_4|gnl|PseudoCAP|PA0420
TIGR NTL03PA00421
UniParc UPI00000C5048
UniProtKB Acc Q9I693
UniProtKB ID Q9I693_PSEAE
UniRef100 UniRef100_Q9I693
UniRef50 UniRef50_P22805
UniRef90 UniRef90_Q9I693

Product

Feature Type CDS
Coding Frame 1
Product Name
adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Product Name Confidence: Class 2
Synonyms 7,8-diamino-pelargonic acid aminotransferase DAPA aminotransferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.91
Kyte-Doolittle Hydrophobicity Value -0.146
Molecular Weight (kDa) 52.5
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 638 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000411 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0420
Search term: bioA

Human Homologs

Ensembl 94, assembly GRCh38.p12
ornithine aminotransferase [Source:HGNC Symbol;Acc:HGNC:8091]
E-value: 8.9e-36
Percent Identity: 28.5

References

Cloning and characterization of the Bacillus sphaericus genes controlling the bioconversion of pimelate into dethiobiotin.
Gloeckler R, Ohsawa I, Speck D, Ledoux C, Bernard S, Zinsius M, Villeval D, Kisou T, Kamogawa K, Lemoine Y
Gene 1990 Mar;87(1):63-70
PubMed ID: 2110099