Pseudomonas aeruginosa PAO1, PA0580 (gcp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0580
Name
gcp
Synonym: ygjD
Replicon chromosome
Genomic location 639316 - 640341 (+ strand)

Cross-References

RefSeq NP_249271.1
GI 15595777
Affymetrix PA0580_gcp_at
DNASU PaCD00006254
Entrez 882271
GenBank AAG03969.1
INSDC AAG03969.1
NCBI Locus Tag PA0580
protein_id(GenBank) gb|AAG03969.1|AE004494_5|gnl|PseudoCAP|PA0580
TIGR NTL03PA00581
UniParc UPI00000C50C5
UniProtKB Acc Q9I5V7
UniProtKB ID TSAD_PSEAE
UniRef100 UniRef100_Q9I5V7
UniRef50 UniRef50_Q4K4W4
UniRef90 UniRef90_A4VHG9

Product

Feature Type CDS
Coding Frame 1
Product Name
O-sialoglycoprotein endopeptidase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.56
Kyte-Doolittle Hydrophobicity Value 0.058
Molecular Weight (kDa) 36.6
Isoelectric Point (pI) 6.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 2
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 665 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000563 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0580
Search term: gcp

Human Homologs

Ensembl 110, assembly GRCh38.p14
O-sialoglycoprotein endopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23075]
E-value: 1.1e-47
Percent Identity: 35.5
Ensembl 110, assembly GRCh38.p14
O-sialoglycoprotein endopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23075]
E-value: 1.1e-47
Percent Identity: 35.5

References

Cloning, nucleotide sequence, and expression of the Pasteurella haemolytica A1 glycoprotease gene.
Abdullah KM, Lo RY, Mellors A
J Bacteriol 1991 Sep;173(18):5597-603
PubMed ID: 1885539