Pseudomonas aeruginosa PAO1, PA0600 (agtS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0600
Name
agtS
Replicon chromosome
Genomic location 660315 - 662708 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249291.1
GI 15595797
Affymetrix PA0600_at
Entrez 880670
GenBank AAG03989.1
INSDC AAG03989.1
NCBI Locus Tag PA0600
protein_id(GenBank) gb|AAG03989.1|AE004496_5|gnl|PseudoCAP|PA0600
TIGR NTL03PA00601
UniParc UPI00000C50D0
UniProtKB Acc Q9I5T8
UniProtKB ID Q9I5T8_PSEAE
UniRef100 UniRef100_Q9I5T8
UniRef50 UniRef50_Q9I5T8
UniRef90 UniRef90_Q9I5T8

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor, AgtS
Product Name Confidence: Class 1
Synonyms probable histidine kinase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -10.76
Kyte-Doolittle Hydrophobicity Value -0.226
Molecular Weight (kDa) 89.5
Isoelectric Point (pI) 5.48

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 508 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000583 (540 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0600
Search term: agtS

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Functional characterization of the agtABCD and agtSR operons for 4-aminobutyrate and 5-aminovalerate uptake and regulation in Pseudomonas aeruginosa PAO1.
Chou HT, Li JY, Lu CD
Curr. Microbiol. 2014 Jan;68(1):59-63
PubMed ID: 23982201