Pseudomonas aeruginosa PAO1, PA1431 (rsaL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1431
Name
rsaL
Replicon chromosome
Genomic location 1558880 - 1559122 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250122.1
GI 15596628
Affymetrix PA1431_rsaL_at
Entrez 881782
GenBank AAG04820.1
INSDC AAG04820.1
NCBI Locus Tag PA1431
protein_id(GenBank) gb|AAG04820.1|AE004572_8|gnl|PseudoCAP|PA1431
TIGR NTL03PA01432
UniParc UPI00000D427F
UniProtKB Acc G3XD78
UniProtKB ID G3XD78_PSEAE
UniRef100 UniRef100_G3XD78
UniRef50 UniRef50_G3XD78
UniRef90 UniRef90_G3XD78

Product

Feature Type CDS
Coding Frame 1
Product Name
regulatory protein RsaL
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.43
Kyte-Doolittle Hydrophobicity Value -0.770
Molecular Weight (kDa) 9.4
Isoelectric Point (pI) 9.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5J2Y GENE REGULATION/DNA 03/30/16 Molecular insight into the regulatory mechanism of the quorum-sensing repressor RsaL in Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA; SYNTHETIC CONSTRUCT 2.4 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001348 (295 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1431
Search term: rsaL

References

The quorum-sensing negative regulator RsaL of Pseudomonas aeruginosa binds to the lasI promoter.
Rampioni G, Bertani I, Zennaro E, Polticelli F, Venturi V, Leoni L
J. Bacteriol. 2006 Jan;188(2):815-9
PubMed ID: 16385073
RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa.
de Kievit T, Seed PC, Nezezon J, Passador L, Iglewski BH
J. Bacteriol. 1999 Apr;181(7):2175-84
PubMed ID: 10094696