Pseudomonas aeruginosa PAO1, PA1483 (cycH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1483
Name
cycH
Replicon chromosome
Genomic location 1608068 - 1609291 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250174.1
GI 15596680
Affymetrix PA1483_cycH_at
Entrez 881742
GenBank AAG04872.1
INSDC AAG04872.1
NCBI Locus Tag PA1483
protein_id(GenBank) gb|AAG04872.1|AE004577_7|gnl|PseudoCAP|PA1483
TIGR NTL03PA01484
UniParc UPI00000C539D
UniProtKB Acc Q9I3M9
UniProtKB ID CYCH_PSEAE
UniRef100 UniRef100_Q9I3M9
UniRef50 UniRef50_Q9I3M9
UniRef90 UniRef90_Q9I3M9

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c-type biogenesis protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (43.29 kDa, PMID:21751344)
Charge (pH 7) -8.50
Kyte-Doolittle Hydrophobicity Value -0.073
Molecular Weight (kDa) 43.3
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Unknown Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 140 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001398 (547 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1483
Search term: cycH

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344