Pseudomonas aeruginosa UCBPP-PA14, PA14_09270 (pchE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_09270
Name
pchE
Replicon chromosome
Genomic location 785708 - 790024 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 29 transposon mutants in orthologs

Cross-References

RefSeq YP_788893.1
GI 116052263
Entrez 4385700
INSDC ABJ13499.1
NCBI Locus Tag PA14_09270
UniParc UPI00000AFB26
UniProtKB Acc Q02T43
UniProtKB ID Q02T43_PSEAB
UniRef100 UniRef100_Q02T43
UniRef50 UniRef50_Q2T477
UniRef90 UniRef90_A0A080VIX7

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydroaeruginoic acid synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -34.51
Kyte-Doolittle Hydrophobicity Value -0.005
Molecular Weight (kDa) 156.5
Isoelectric Point (pI) 4.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7EMY LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module Pseudomonas aeruginosa PAO1 2.97 ELECTRON MICROSCOPY 99.0
7EN2 LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation, condensation Pseudomonas aeruginosa PAO1 3.78 ELECTRON MICROSCOPY 99.0
7EN1 LIGASE 04/15/21 Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation Pseudomonas aeruginosa PAO1 3.47 ELECTRON MICROSCOPY 99.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001483 (2117 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_09270
Search term: pchE

Human Homologs

Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 3.5e-13
Percent Identity: 28.6

References

No references are associated with this feature.