Pseudomonas aeruginosa UCBPP-PA14, PA14_18140 (mmsB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_18140
Name	mmsB
Replicon	chromosome
Genomic location	1556038 - 1556934 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	5 transposon mutants in orthologs

Cross-References

RefSeq	YP_789596.1
GI	116051566
Entrez	4381532
INSDC	ABJ12802.1
NCBI Locus Tag	PA14_18140
UniParc	UPI00003960FA
UniProtKB Acc	Q02R40
UniProtKB ID	Q02R40_PSEAB
UniRef100	UniRef100_Q02R40
UniRef50	UniRef50_Q9I5I6
UniRef90	UniRef90_P28811

Product

Feature Type	CDS
Coding Frame	1
Product Name	3-hydroxyisobutyrate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.69
Kyte-Doolittle Hydrophobicity Value	0.201
Molecular Weight (kDa)	30.5
Isoelectric Point (pI)	6.51

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 473 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000717 (830 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_18140 Search term: mmsB Search term: 3-hydroxyisobutyrate dehydrogenase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000265395 3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907] E-value: 2.4e-62 Percent Identity: 43.4

References