Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_18580
|
Name |
algD
|
Replicon | chromosome |
Genomic location | 1593998 - 1595308 (- strand) |
Transposon Mutants | 1 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | YP_789625.1 |
GI | 116051539 |
Entrez | 4381505 |
INSDC | ABJ12775.1 |
NCBI Locus Tag | PA14_18580 |
UniParc | UPI000012584C |
UniProtKB Acc | Q02R11 |
UniProtKB ID | Q02R11_PSEAB |
UniRef100 | UniRef100_P11759 |
UniRef50 | UniRef50_P11759 |
UniRef90 | UniRef90_P11759 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GDP-mannose 6-dehydrogenase AlgD
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -9.09 |
Kyte-Doolittle Hydrophobicity Value | -0.051 |
Molecular Weight (kDa) | 47.6 |
Isoelectric Point (pI) | 5.35 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
1MV8 | OXIDOREDUCTASE | 09/24/02 | 1.55 A crystal structure of a ternary complex of GDP-mannose dehydrogenase from Psuedomonas aeruginosa | Pseudomonas aeruginosa | 1.55 | X-RAY DIFFRACTION | 100.0 |
1MFZ | OXIDOREDUCTASE | 08/14/02 | Partially refined 2.8 A Crystal structure of GDP-mannose dehydrogenase from P. aeruginosa | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 100.0 |
1MUU | OXIDOREDUCTASE | 09/24/02 | 2.0 A crystal structure of GDP-mannose dehydrogenase | Pseudomonas aeruginosa | 2.02 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
Guanosine 5'-(Trihydrogen Diphosphate), P'-D-Mannopyranosyl Ester | DB04023 | DrugBank | 5.1.4 | P11759 | GDP-mannose 6-dehydrogenase | 100.0 | 436 | 7.2e-252 |
Sucrose | DB02772 | DrugBank | 5.1.4 | P11759 | GDP-mannose 6-dehydrogenase | 100.0 | 436 | 7.2e-252 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 588 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002126 (490 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_18580
Search term: algD
Search term: GDP-mannose 6-dehydrogenase AlgD
|