Pseudomonas aeruginosa UCBPP-PA14, PA14_20610 (lecB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_20610
Name	lecB
Replicon	chromosome
Genomic location	1773860 - 1774207 (- strand)
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_789791.1
GI	116051376
Entrez	4382274
INSDC	ABJ12612.1
NCBI Locus Tag	PA14_20610
UniParc	UPI0000E44982
UniProtKB Acc	Q02QJ5
UniProtKB ID	Q02QJ5_PSEAB
UniRef100	UniRef100_Q02QJ5
UniRef50	UniRef50_Q02QJ5
UniRef90	UniRef90_Q02QJ5

Product

Feature Type	CDS
Coding Frame	1
Product Name	fucose-binding lectin PA-IIL
Synonyms
Evidence for Translation
Charge (pH 7)	-5.02
Kyte-Doolittle Hydrophobicity Value	0.140
Molecular Weight (kDa)	11.8
Isoelectric Point (pI)	3.83

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
5A6Z	SUGAR BINDING PROTEIN	07/02/15	Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with lewis a	PSEUDOMONAS AERUGINOSA	1.5	X-RAY DIFFRACTION	100.0
5A6Y	HYDROLASE	07/02/15	Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with mannose-alpha1,3mannoside	PSEUDOMONAS AERUGINOSA	1.4	X-RAY DIFFRACTION	100.0
5A70	SUGAR BINDING PROTEIN	07/02/15	Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with lewis x tetrasaccharide	PSEUDOMONAS AERUGINOSA	1.6	X-RAY DIFFRACTION	100.0
5A6Q	SUGAR BINDING PROTEIN	06/30/15	Native structure of the LecB lectin from Pseudomonas aeruginosa strain PA14	PSEUDOMONAS AERUGINOSA	1.7	X-RAY DIFFRACTION	100.0
5A6X	SUGAR BINDING PROTEIN	07/02/15	Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with alpha-methyl-fucoside	PSEUDOMONAS AERUGINOSA	1.55	X-RAY DIFFRACTION	100.0
5MB1	SUGAR BINDING PROTEIN	11/07/16	STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2,4,6-Trimethylphenylsulfonamide-N-methyl-L-fucopyranoside	Pseudomonas aeruginosa (strain UCBPP-PA14)	1.65	X-RAY DIFFRACTION	100.0
5MAY	SUGAR BINDING PROTEIN	11/07/16	STRUCTURE OF THE LECB LECTIN FROM PSEUDOMONAS AERUGINOSA STRAIN PA14 IN COMPLEX WITH 2-Thiophenesulfonamide-N-(beta-L-fucopyranosyl methyl)	Pseudomonas aeruginosa (strain UCBPP-PA14)	1.65	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 6 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002267 (300 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_20610 Search term: lecB Search term: fucose-binding lectin PA-IIL

Human Homologs

References