Pseudomonas aeruginosa UCBPP-PA14, PA14_22000 (rluA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_22000
Name	rluA
Replicon	chromosome
Genomic location	1913806 - 1914441 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_789909.1
GI	116051259
Entrez	4381244
INSDC	ABJ12495.1
NCBI Locus Tag	PA14_22000
UniParc	UPI0000396014
UniProtKB Acc	Q02Q77
UniProtKB ID	Q02Q77_PSEAB
UniRef100	UniRef100_Q02Q77
UniRef50	UniRef50_A4SR76
UniRef90	UniRef90_S6ASJ3

Product

Feature Type	CDS
Coding Frame	1
Product Name	pseudouridine synthase
Synonyms
Evidence for Translation
Charge (pH 7)	0.24
Kyte-Doolittle Hydrophobicity Value	-0.472
Molecular Weight (kDa)	24.3
Isoelectric Point (pI)	7.04

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002362 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_22000 Search term: rluA Search term: pseudouridine synthase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000433065 RNA pseudouridine synthase D4 [Source:HGNC Symbol;Acc:HGNC:25898] E-value: 2.7e-15 Percent Identity: 33.0

References