Pseudomonas aeruginosa UCBPP-PA14, PA14_23500 (tyrB)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_23500
Name	tyrB
Replicon	chromosome
Genomic location	2044344 - 2045540 (- strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	4 transposon mutants in orthologs

Cross-References

RefSeq	YP_790034.1
GI	116051135
EC Number	2.6.1.57
Entrez	4381139
INSDC	ABJ12371.1
NCBI Locus Tag	PA14_23500
UniParc	UPI0000E449CA
UniProtKB Acc	Q02PV2
UniProtKB ID	Q02PV2_PSEAB
UniRef100	UniRef100_S0IEJ3
UniRef50	UniRef50_O85746
UniRef90	UniRef90_P72173

Product

Feature Type	CDS
Coding Frame	1
Product Name	aromatic amino acid aminotransferase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.40
Kyte-Doolittle Hydrophobicity Value	-0.058
Molecular Weight (kDa)	43.3
Isoelectric Point (pI)	6.64

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 166 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002461 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_23500 Search term: tyrB Search term: aromatic amino acid aminotransferase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000245206 glutamic-oxaloacetic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4433] E-value: 8.2e-90 Percent Identity: 43.2

References