Pseudomonas aeruginosa UCBPP-PA14, PA14_23790 (leuB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_23790
Name
leuB
Replicon chromosome
Genomic location 2066538 - 2067620 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_790055.1
GI 116051114
EC Number 1.1.1.85
Entrez 4381118
INSDC ABJ12350.1
NCBI Locus Tag PA14_23790
UniParc UPI000012E55B
UniProtKB Acc Q02PT1
UniProtKB ID Q02PT1_PSEAB
UniRef100 UniRef100_Q51375
UniRef50 UniRef50_Q56268
UniRef90 UniRef90_Q51375

Product

Feature Type CDS
Coding Frame 1
Product Name
3-isopropylmalate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -9.36
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 39.1
Isoelectric Point (pI) 4.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002480 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_23790
Search term: leuB

Human Homologs

Ensembl 110, assembly GRCh38.p14
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:5385]
E-value: 1.8e-27
Percent Identity: 29.2

References

No references are associated with this feature.