Pseudomonas aeruginosa UCBPP-PA14, PA14_24220 (ppnK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_24220
Name
ppnK
Replicon chromosome
Genomic location 2101330 - 2102217 (+ strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_790085.1
GI 116051084
EC Number 2.7.1.23
Entrez 4384119
INSDC ABJ12320.1
NCBI Locus Tag PA14_24220
UniParc UPI00001320BE
UniProtKB Acc Q02PQ1
UniProtKB ID NADK_PSEAB
UniRef100 UniRef100_A6V2Y8
UniRef50 UniRef50_Q4KBJ2
UniRef90 UniRef90_A6V2Y8

Product

Feature Type CDS
Coding Frame 1
Product Name
inorganic polyphosphate/ATP-NAD kinase
Synonyms
Evidence for Translation
Charge (pH 7) 1.22
Kyte-Doolittle Hydrophobicity Value 0.017
Molecular Weight (kDa) 32.1
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7QVS STRUCTURAL PROTEIN 01/23/22 Pseudomonas aeruginosa nicotinamide adenine dinucleotide kinase (NADK) structure in complex with NADP Pseudomonas aeruginosa 2.3 X-RAY DIFFRACTION 100.0
7MH7 TRANSFERASE 04/14/21 crystal structure of NAD kinase from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 2.61 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 647 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002504 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_24220
Search term: ppnK

Human Homologs

Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5
Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5
Ensembl 110, assembly GRCh38.p14
NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]
E-value: 1.1e-33
Percent Identity: 28.5

References

No references are associated with this feature.