Pseudomonas aeruginosa UCBPP-PA14, PA14_24640 (pyrD)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_24640
Name	pyrD
Replicon	chromosome
Genomic location	2153624 - 2154652 (+ strand)
Transposon Mutants	3 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_790121.1
GI	116051050
EC Number	1.3.3.1
EC Number	1.3.98.1
Entrez	4381074
INSDC	ABJ12286.1
NCBI Locus Tag	PA14_24640
UniParc	UPI0000395F91
UniProtKB Acc	Q02PL5
UniProtKB ID	PYRD_PSEAB
UniRef100	UniRef100_Q02PL5
UniRef50	UniRef50_P57443
UniRef90	UniRef90_A6V325

Product

Feature Type	CDS
Coding Frame	1
Product Name	dihydroorotate dehydrogenase 2
Synonyms
Evidence for Translation
Charge (pH 7)	1.66
Kyte-Doolittle Hydrophobicity Value	0.030
Molecular Weight (kDa)	36.1
Isoelectric Point (pI)	7.79

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002538 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_24640 Search term: pyrD Search term: dihydroorotate dehydrogenase 2

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000219240 dihydroorotate dehydrogenase (quinone) [Source:HGNC Symbol;Acc:HGNC:2867] E-value: 2.9e-67 Percent Identity: 43.8

References