Pseudomonas aeruginosa PAO1, PA2835

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2835
Name
Replicon chromosome
Genomic location 3187546 - 3189138 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251525.1
GI 15598031
Affymetrix PA2835_at
Entrez 882807
GenBank AAG06223.1
INSDC AAG06223.1
NCBI Locus Tag PA2835
protein_id(GenBank) gb|AAG06223.1|AE004710_5|gnl|PseudoCAP|PA2835
TIGR NTL03PA02835
UniParc UPI00000C5833
UniProtKB Acc Q9I008
UniProtKB ID Q9I008_PSEAE
UniRef100 UniRef100_W0YTZ1
UniRef50 UniRef50_B4SIV4
UniRef90 UniRef90_A6V3Q5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 2.00
Kyte-Doolittle Hydrophobicity Value 0.734
Molecular Weight (kDa) 56.8
Isoelectric Point (pI) 7.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 409 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002732 (459 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2835

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Multidrug resistance pumps in bacteria: variations on a theme.
Lewis K
Trends Biochem Sci 1994 Mar;19(3):119-23
PubMed ID: 8203018