Pseudomonas aeruginosa PAO1, PA2859 (greB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2859
Name
greB
Replicon chromosome
Genomic location 3212525 - 3213031 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_251549.1
GI 15598055
Affymetrix PA2859_greB_at
DNASU PaCD00007245
Entrez 879611
GenBank AAG06247.1
INSDC AAG06247.1
NCBI Locus Tag PA2859
protein_id(GenBank) gb|AAG06247.1|AE004712_7|gnl|PseudoCAP|PA2859
TIGR NTL03PA02859
UniParc UPI000012BAC2
UniProtKB Acc Q9HZY5
UniProtKB ID GREB_PSEAE
UniRef100 UniRef100_Q9HZY5
UniRef50 UniRef50_Q9HZY5
UniRef90 UniRef90_Q9HZY5

Product

Feature Type CDS
Coding Frame 1
Product Name
transcription elongation factor GreB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.52
Kyte-Doolittle Hydrophobicity Value -0.550
Molecular Weight (kDa) 19.1
Isoelectric Point (pI) 6.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002710 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2859
Search term: greB

Human Homologs

References

Transcript cleavage factors from E. coli.
Borukhov S, Sagitov V, Goldfarb A
Cell 1993 Feb 12;72(3):459-66
PubMed ID: 8431948