Pseudomonas aeruginosa PAO1, PA2973

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2973
Name
Replicon chromosome
Genomic location 3329690 - 3330670 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251663.1
GI 15598169
Affymetrix PA2973_at
DNASU PaCD00007298
Entrez 879106
GenBank AAG06361.1
INSDC AAG06361.1
NCBI Locus Tag PA2973
protein_id(GenBank) gb|AAG06361.1|AE004723_5|gnl|PseudoCAP|PA2973
TIGR NTL03PA02973
UniParc UPI00000C58AD
UniProtKB Acc Q9HZN1
UniProtKB ID Q9HZN1_PSEAE
UniRef100 UniRef100_A0A073A4X2
UniRef50 UniRef50_Q4KFS3
UniRef90 UniRef90_A0A073A4X2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable peptidase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (36.06 kDa, PMID:21751344)
Charge (pH 7) 2.21
Kyte-Doolittle Hydrophobicity Value -0.273
Molecular Weight (kDa) 36.1
Isoelectric Point (pI) 8.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 488 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002609 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2973

Human Homologs

References

Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344