Pseudomonas aeruginosa PAO1, PA3120 (leuD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3120
Name
leuD
Replicon chromosome
Genomic location 3502642 - 3503280 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251810.1
GI 15598316
Affymetrix PA3120_leuD_at
Entrez 882818
GenBank AAG06508.1
INSDC AAG06508.1
NCBI Locus Tag PA3120
protein_id(GenBank) gb|AAG06508.1|AE004736_5|gnl|PseudoCAP|PA3120
TIGR NTL03PA03120
UniParc UPI000012E596
UniProtKB Acc Q9HZA4
UniProtKB ID LEUD_PSEAE
UniRef100 UniRef100_B7VBQ0
UniRef50 UniRef50_P96196
UniRef90 UniRef90_B7VBQ0

Product

Feature Type CDS
Coding Frame 1
Product Name
3-isopropylmalate dehydratase small subunit
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.58
Kyte-Doolittle Hydrophobicity Value -0.438
Molecular Weight (kDa) 24.0
Isoelectric Point (pI) 4.67

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002478 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3120
Search term: leuD

Human Homologs

References

Characterization of the 3' end of the leucine operon of Salmonella typhimurium.
Friedberg D, Rosenthal ER, Jones JW, Calvo JM
Mol Gen Genet 1985;199(3):486-94
PubMed ID: 2993799