Pseudomonas aeruginosa PAO1, PA3131

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3131
Name
Synonym: edaB
Replicon chromosome
Genomic location 3512394 - 3513041 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251821.1
GI 15598327
Affymetrix PA3131_at
DNASU PaCD00007375
Entrez 879952
GenBank AAG06519.1
INSDC AAG06519.1
NCBI Locus Tag PA3131
protein_id(GenBank) gb|AAG06519.1|AE004737_5|gnl|PseudoCAP|PA3131
TIGR NTL03PA03131
UniParc UPI00000C5920
UniProtKB Acc Q9HZ93
UniProtKB ID Q9HZ93_PSEAE
UniRef100 UniRef100_U8NFG5
UniRef50 UniRef50_A0A090EM90
UniRef90 UniRef90_B7VBN9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aldolase
Product Name Confidence: Class 3
Synonyms 2-keto-3-deoxy-6-phosphogluconate aldolase
4-hydroxy-2-oxoglutarate aldolase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.38
Kyte-Doolittle Hydrophobicity Value 0.299
Molecular Weight (kDa) 22.9
Isoelectric Point (pI) 5.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 371 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002467 (329 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3131
Search term: probable aldolase

Human Homologs

References

Active-site residues of 2-keto-4-hydroxyglutarate aldolase from Escherichia coli. Bromopyruvate inactivation and labeling of glutamate 45.
Vlahos CJ, Dekker EE
J Biol Chem 1990 Nov 25;265(33):20384-9
PubMed ID: 1978721