Pseudomonas aeruginosa PAO1, PA3146 (wbpK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3146
Name
wbpK
Replicon chromosome
Genomic location 3529508 - 3530458 (- strand)

Cross-References

RefSeq NP_251836.1
GI 15598342
Affymetrix PA3146_wbpK_at
DNASU PaCD00007383
Entrez 882698
GenBank AAG06534.1
NCBI Locus Tag PA3146
protein_id(GenBank) gb|AAG06534.1|AE004738_8|gnl|PseudoCAP|PA3146
TIGR NTL03PA03146
UniProtKB Acc Q9HZ81
UniProtKB ID Q9HZ81_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable NAD-dependent epimerase/dehydratase WbpK
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.02
Kyte-Doolittle Hydrophobicity Value 0.153
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 8.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 575 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002457 (402 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3146
Search term: wbpK

Human Homologs

References

Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
Burrows LL, Charter DF, Lam JS
Mol Microbiol 1996 Nov;22(3):481-95
PubMed ID: 8939432