Pseudomonas aeruginosa PAO1, PA3327

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3327
Name
Replicon chromosome
Genomic location 3730557 - 3737615 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_252017.1
GI 15598523
Affymetrix PA3327_at
Entrez 882492
GenBank AAG06715.1
INSDC AAG06715.1
NCBI Locus Tag PA3327
protein_id(GenBank) gb|AAG06715.1|AE004755_2|gnl|PseudoCAP|PA3327
TIGR NTL03PA03327
UniParc UPI00000C59B6
UniProtKB Acc Q9HYR8
UniProtKB ID Q9HYR8_PSEAE
UniRef100 UniRef100_Q9HYR8
UniRef50 UniRef50_A0A077JXG4
UniRef90 UniRef90_A0A077JXG4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable non-ribosomal peptide synthetase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -52.26
Kyte-Doolittle Hydrophobicity Value -0.100
Molecular Weight (kDa) 259.4
Isoelectric Point (pI) 5.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 579 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001483 (2117 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3327

Human Homologs

Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 2.5e-29
Percent Identity: 26.0
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 2.5e-29
Percent Identity: 26.0
Ensembl 110, assembly GRCh38.p14
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 2.5e-29
Percent Identity: 26.0

References

No references are associated with this feature.