Pseudomonas aeruginosa PAO1, PA3330

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3330
Name
Replicon chromosome
Genomic location 3740105 - 3741019 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252020.1
GI 15598526
Affymetrix PA3330_at
Entrez 882495
GenBank AAG06718.1
INSDC AAG06718.1
NCBI Locus Tag PA3330
protein_id(GenBank) gb|AAG06718.1|AE004755_5|gnl|PseudoCAP|PA3330
TIGR NTL03PA03330
UniParc UPI00000C59B9
UniProtKB Acc Q9HYR5
UniProtKB ID Q9HYR5_PSEAE
UniRef100 UniRef100_W0YX55
UniRef50 UniRef50_K0K131
UniRef90 UniRef90_W0YX55

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.63
Kyte-Doolittle Hydrophobicity Value 0.051
Molecular Weight (kDa) 32.0
Isoelectric Point (pI) 8.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001308 (593 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3330

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]
E-value: 4.0e-36
Percent Identity: 37.3
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]
E-value: 4.0e-36
Percent Identity: 37.3
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]
E-value: 4.0e-36
Percent Identity: 37.3
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]
E-value: 4.0e-36
Percent Identity: 37.3
Ensembl 110, assembly GRCh38.p14
hydroxysteroid 17-beta dehydrogenase 6 [Source:HGNC Symbol;Acc:HGNC:23316]
E-value: 4.0e-36
Percent Identity: 37.3

References

Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation.
Mertz JR, Shang E, Piantedosi R, Wei S, Wolgemuth DJ, Blaner WS
J Biol Chem 1997 May 2;272(18):11744-9
PubMed ID: 9115228