Pseudomonas aeruginosa PAO1, PA3826

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3826
Name
Replicon chromosome
Genomic location 4283788 - 4284285 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252515.1
GI 15599021
Affymetrix PA3826_at
DNASU PaCD00007667
Entrez 879871
GenBank AAG07213.1
INSDC AAG07213.1
NCBI Locus Tag PA3826
protein_id(GenBank) gb|AAG07213.1|AE004800_2|gnl|PseudoCAP|PA3826
TIGR NTL03PA03826
UniParc UPI00000C5B2B
UniProtKB Acc Q9HXH6
UniProtKB ID Q9HXH6_PSEAE
UniRef100 UniRef100_Q9HXH6
UniRef50 UniRef50_L8M870
UniRef90 UniRef90_Q9HXH6

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 8.12
Kyte-Doolittle Hydrophobicity Value 0.259
Molecular Weight (kDa) 18.9
Isoelectric Point (pI) 10.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database Victors : 4239
Category
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Rattus norvegicus
Notes
Infection model Rat agar bead model of chronic lung infection
Reference 14641575

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 115 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001839 (510 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3826

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
A 10 kb nucleotide sequence at the 5' flanking region (32 degrees) of srfAA of the Bacillus subtilis chromosome.
Fujishima Y, Yamane K
Microbiology (Reading) 1995 Feb;141 ( Pt 2):277-9
PubMed ID: 7704255