Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3908
|
Name |
tsiT
Synonym: type VI immunity for Tox-Rease |
Replicon | chromosome |
Genomic location | 4376012 - 4376731 (+ strand) |
Transposon Mutants | 1 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_252597.1 |
GI | 15599103 |
Affymetrix | PA3908_at |
Entrez | 878965 |
GenBank | AAG07295.1 |
INSDC | AAG07295.1 |
NCBI Locus Tag | PA3908 |
protein_id(GenBank) | gb|AAG07295.1|AE004808_5|gnl|PseudoCAP|PA3908 |
TIGR | NTL03PA03908 |
UniParc | UPI00000C5B6E |
UniProtKB Acc | Q9HXA5 |
UniProtKB ID | Q9HXA5_PSEAE |
UniRef100 | UniRef100_Q9HXA5 |
UniRef50 | UniRef50_Q9HXA5 |
UniRef90 | UniRef90_Q9HXA5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
immunity protein, TsiT
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.13 |
Kyte-Doolittle Hydrophobicity Value | -0.292 |
Molecular Weight (kDa) | 27.3 |
Isoelectric Point (pI) | 5.04 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6JDP | ANTITOXIN | 02/02/19 | the imm52 family protein TsiT (PA3908) from Pseudomonas aeruginosa | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.601 | X-RAY DIFFRACTION | 100.0 |
7DYM | TOXIN | 01/22/21 | Pseudomonas aeruginosa TseT-TsiT complex | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.1 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 7 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001768 (310 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3908
Search term: tsiT
Search term: immunity protein, TsiT
|
A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex.
Burkinshaw BJ, Liang X, Wong M, Le ANH, Lam L, Dong TG
Nat Microbiol 2018 May;3(5):632-640
PubMed ID: 29632369
|