Pseudomonas aeruginosa PAO1, PA4120

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4120
Name
Replicon chromosome
Genomic location 4608436 - 4609347 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252809.1
GI 15599315
Affymetrix PA4120_at
DNASU PaCD00007795
Entrez 880227
GenBank AAG07507.1
INSDC AAG07507.1
NCBI Locus Tag PA4120
protein_id(GenBank) gb|AAG07507.1|AE004828_8|gnl|PseudoCAP|PA4120
TIGR NTL03PA04120
UniParc UPI00000C5C1D
UniProtKB Acc Q9HWR1
UniProtKB ID Q9HWR1_PSEAE
UniRef100 UniRef100_W0YYE0
UniRef50 UniRef50_Q4KBA9
UniRef90 UniRef90_A6UZX3

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transcriptional regulator
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 3.83
Kyte-Doolittle Hydrophobicity Value -0.273
Molecular Weight (kDa) 34.3
Isoelectric Point (pI) 8.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 243 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000246 (890 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4120

Human Homologs

References

Molecular characterization of 4-hydroxyphenylacetate 3-hydroxylase of Escherichia coli. A two-protein component enzyme.
Prieto MA, Garcia JL
J Biol Chem 1994 Sep 9;269(36):22823-9
PubMed ID: 8077235
Molecular characterization of the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli W: engineering a mobile aromatic degradative cluster.
Prieto MA, Díaz E, García JL
J Bacteriol 1996 Jan;178(1):111-20
PubMed ID: 8550403