Pseudomonas aeruginosa PAO1, PA4289

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4289
Name
Replicon chromosome
Genomic location 4811396 - 4812601 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_252979.1
GI 15599485
Affymetrix PA4289_at
Entrez 881647
GenBank AAG07677.1
INSDC AAG07677.1
NCBI Locus Tag PA4289
protein_id(GenBank) gb|AAG07677.1|AE004845_3|gnl|PseudoCAP|PA4289
TIGR NTL03PA04290
UniParc UPI00000C5C9A
UniProtKB Acc Q9HWB1
UniProtKB ID Q9HWB1_PSEAE
UniRef100 UniRef100_Q9HWB1
UniRef50 UniRef50_Q3J447
UniRef90 UniRef90_A0A077JMA7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 7.46
Kyte-Doolittle Hydrophobicity Value 0.820
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 8.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 321 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003892 (394 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4289

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295