Pseudomonas aeruginosa PAO1, PA4480 (mreC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA4480
Name
mreC
Replicon chromosome
Genomic location 5011322 - 5012314 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_253170.1
GI 15599676
Affymetrix PA4480_mreC_at
Entrez 881172
GenBank AAG07868.1
INSDC AAG07868.1
NCBI Locus Tag PA4480
protein_id(GenBank) gb|AAG07868.1|AE004862_2|gnl|PseudoCAP|PA4480
TIGR NTL03PA04481
UniParc UPI00000C5D2D
UniProtKB Acc Q9HVU1
UniProtKB ID Q9HVU1_PSEAE
UniRef100 UniRef100_Q9HVU1
UniRef50 UniRef50_Q9HVU1
UniRef90 UniRef90_Q9HVU1

Product

Feature Type CDS
Coding Frame 1
Product Name
rod shape-determining protein MreC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Detected using LC-MS/MS (35.23 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.51
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 35.2
Isoelectric Point (pI) 5.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 392 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004069 (546 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4480
Search term: mreC

References

Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells.
Doi M, Wachi M, Ishino F, Tomioka S, Ito M, Sakagami Y, Suzuki A, Matsuhashi M
J Bacteriol 1988 Oct;170(10):4619-24
PubMed ID: 3049542
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344