Pseudomonas aeruginosa PAO1, PA5053 (hslV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5053
Name
hslV
Replicon chromosome
Genomic location 5692576 - 5693109 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253740.1
GI 15600246
Affymetrix PA5053_hslV_at
DNASU PaCD00008172
Entrez 881049
GenBank AAG08438.1
INSDC AAG08438.1
NCBI Locus Tag PA5053
protein_id(GenBank) gb|AAG08438.1|AE004918_8|gnl|PseudoCAP|PA5053
TIGR NTL03PA05054
UniParc UPI0000165ED9
UniProtKB Acc Q9HUC6
UniProtKB ID HSLV_PSEAE
UniRef100 UniRef100_B7V3E6
UniRef50 UniRef50_Q9WYZ1
UniRef90 UniRef90_A6VDH4

Product

Feature Type CDS
Coding Frame 1
Product Name
heat shock protein HslV
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
Charge (pH 7) -0.83
Kyte-Doolittle Hydrophobicity Value 0.040
Molecular Weight (kDa) 18.8
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 364 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004655 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5053
Search term: hslV

Human Homologs

References

Sequence analysis of four new heat-shock genes constituting the hslTS/ibpAB and hslVU operons in Escherichia coli.
Chuang SE, Burland V, Plunkett G 3rd, Daniels DL, Blattner FR
Gene 1993 Nov 30;134(1):1-6
PubMed ID: 8244018
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142