Pseudomonas aeruginosa PAO1, PA5450 (wzt)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA5450
Name
wzt
Replicon chromosome
Genomic location 6139604 - 6140869 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254137.1
GI 15600643
Affymetrix PA5450_wzt_at
Entrez 883117
GenBank AAG08835.1
INSDC AAG08835.1
NCBI Locus Tag PA5450
protein_id(GenBank) gb|AAG08835.1|AE004958_5|gnl|PseudoCAP|PA5450
TIGR NTL03PA05451
UniParc UPI00000D4269
UniProtKB Acc G3XD58
UniProtKB ID G3XD58_PSEAE
UniRef100 UniRef100_G3XD58
UniRef50 UniRef50_G3XD58
UniRef90 UniRef90_G3XD58

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC subunit of A-band LPS efflux transporter
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.42
Kyte-Doolittle Hydrophobicity Value -0.174
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 6.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001312 (616 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5450
Search term: wzt

Human Homologs

Ensembl 94, assembly GRCh38.p12
ATP binding cassette subfamily A member 8 [Source:HGNC Symbol;Acc:HGNC:38]
E-value: 6.8e-19
Percent Identity: 27.8

References

Identification and functional characterization of an ABC transport system involved in polysaccharide export of A-band lipopolysaccharide in Pseudomonas aeruginosa.
Rocchetta HL, Lam JS
J. Bacteriol. 1997 Aug;179(15):4713-24
PubMed ID: 9244257