Pseudomonas aeruginosa PAO1, PA0367 (laoR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0367
Name
laoR
Replicon chromosome
Genomic location 411224 - 411871 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentA laoR deletion mutant exhibited constitutive expression of LaoA and LaoB, indicating that LaoR is a repressor for the expression of laoABC (PMID:29678916).
CommentAdjacent to the Lao (long-chain-alcohol/aldehyde-oxidation) gene cluster (laoABC).

Cross-References

RefSeq NP_249058.1
GI 15595564
Affymetrix PA0367_at
Entrez 880928
GenBank AAG03756.1
INSDC AAG03756.1
NCBI Locus Tag PA0367
protein_id(GenBank) gb|AAG03756.1|AE004474_8|gnl|PseudoCAP|PA0367
TIGR NTL03PA00368
UniParc UPI00000C502B
UniProtKB Acc Q9I6C7
UniProtKB ID Q9I6C7_PSEAE
UniRef100 UniRef100_W0YLD2
UniRef50 UniRef50_Q4K4B1
UniRef90 UniRef90_W0YLD2

Product

Feature Type CDS
Coding Frame 1
Product Name
LaoR
Product Name Confidence: Class 1
Synonyms probable transcriptional regulator
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.38
Kyte-Doolittle Hydrophobicity Value -0.145
Molecular Weight (kDa) 24.5
Isoelectric Point (pI) 5.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 143 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000358 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0367
Search term: laoR
Search term: LaoR

References

PubMed ID: 29678916