Pseudomonas aeruginosa PAO1, PA0375 (ftsX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0375
Name
ftsX
Replicon chromosome
Genomic location 419562 - 420569 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249066.1
GI 15595572
Affymetrix PA0375_ftsX_at
Entrez 883092
GenBank AAG03764.1
INSDC AAG03764.1
NCBI Locus Tag PA0375
protein_id(GenBank) gb|AAG03764.1|AE004475_6|gnl|PseudoCAP|PA0375
TIGR NTL03PA00376
UniParc UPI00000C5033
UniProtKB Acc Q9I6B9
UniProtKB ID Q9I6B9_PSEAE
UniRef100 UniRef100_W0YJW1
UniRef50 UniRef50_Q9R9Y4
UniRef90 UniRef90_A6UYI0

Product

Feature Type CDS
Coding Frame 1
Product Name
cell division protein FtsX
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (36.93 kDa, PMID:21751344)
Charge (pH 7) -5.82
Kyte-Doolittle Hydrophobicity Value 0.050
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 338 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000366 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0375
Search term: ftsX

References

A new cell division operon in Escherichia coli.
Gill DR, Hatfull GF, Salmond GP
Mol. Gen. Genet. 1986 Oct;205(1):134-45
PubMed ID: 3025556
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344