Pseudomonas aeruginosa PAO1, PA0455 (dbpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA0455
Name
dbpA
Replicon chromosome
Genomic location 513051 - 514427 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249146.1
GI 15595652
Affymetrix PA0455_dbpA_at
Entrez 881459
GenBank AAG03844.1
INSDC AAG03844.1
NCBI Locus Tag PA0455
protein_id(GenBank) gb|AAG03844.1|AE004483_2|gnl|PseudoCAP|PA0455
TIGR NTL03PA00456
UniParc UPI00000C5065
UniProtKB Acc Q9I663
UniProtKB ID Q9I663_PSEAE
UniRef100 UniRef100_Q9I663
UniRef50 UniRef50_P21693
UniRef90 UniRef90_Q9I663

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA helicase DbpA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.18
Kyte-Doolittle Hydrophobicity Value -0.034
Molecular Weight (kDa) 49.8
Isoelectric Point (pI) 8.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000446 (550 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0455
Search term: dbpA
Search term: RNA helicase DbpA

Human Homologs

Ensembl 97, assembly GRCh38.p12
DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]
E-value: 7.2e-62
Percent Identity: 40.3

Human Homologs

Ensembl 97, assembly GRCh38.p12
DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]
E-value: 7.2e-62
Percent Identity: 40.3

Human Homologs

Ensembl 97, assembly GRCh38.p12
DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]
E-value: 7.2e-62
Percent Identity: 40.3

Human Homologs

Ensembl 97, assembly GRCh38.p12
DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]
E-value: 7.2e-62
Percent Identity: 40.3

Human Homologs

Ensembl 97, assembly GRCh38.p12
DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]
E-value: 7.2e-62
Percent Identity: 40.3

References

DbpA: a DEAD box protein specifically activated by 23s rRNA.
Fuller-Pace FV, Nicol SM, Reid AD, Lane DP
EMBO J. 1993 Sep;12(9):3619-26
PubMed ID: 8253085
Characterization of DbpA, an Escherichia coli DEAD box protein with ATP independent RNA unwinding activity.
Böddeker N, Stade K, Franceschi F
Nucleic Acids Res. 1997 Feb;25(3):537-45
PubMed ID: 9016593
Cloning and biochemical characterization of Bacillus subtilis YxiN, a DEAD protein specifically activated by 23S rRNA: delineation of a novel sub-family of bacterial DEAD proteins.
Kossen K, Uhlenbeck OC
Nucleic Acids Res. 1999 Oct;27(19):3811-20
PubMed ID: 10481020