Pseudomonas aeruginosa PAO1, PA1458

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1458
Name
Synonym: cheA
Replicon chromosome
Genomic location 1587023 - 1589284 (+ strand)
Transposon Mutants 7 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_250149.1
GI 15596655
Affymetrix PA1458_at
Entrez 882057
GenBank AAG04847.1
INSDC AAG04847.1
NCBI Locus Tag PA1458
protein_id(GenBank) gb|AAG04847.1|AE004575_6|gnl|PseudoCAP|PA1458
TIGR NTL03PA01459
UniParc UPI00000D4215
UniProtKB Acc G3XCT6
UniProtKB ID G3XCT6_PSEAE
UniRef100 UniRef100_G3XCT6
UniRef50 UniRef50_Q4KG37
UniRef90 UniRef90_Q02JU2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms probable chemotaxis signal transduction histidine kinase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -51.35
Kyte-Doolittle Hydrophobicity Value -0.054
Molecular Weight (kDa) 79.7
Isoelectric Point (pI) 4.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001373 (520 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1458

References

Identification of a chemotaxis gene region from Pseudomonas putida.
Ditty JL, Grimm AC, Harwood CS
FEMS Microbiol. Lett. 1998 Feb;159(2):267-73
PubMed ID: 9503621
Structure of CheA, a signal-transducing histidine kinase.
Bilwes AM, Alex LA, Crane BR, Simon MI
Cell 1999 Jan;96(1):131-41
PubMed ID: 9989504