Pseudomonas aeruginosa PAO1, PA1477 (ccmC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1477
Name
ccmC
Synonym: helC
Synonym: cycZ
Synonym: pfcyt1
Replicon chromosome
Genomic location 1603671 - 1604429 (+ strand)

Cross-References

RefSeq NP_250168.1
GI 15596674
Affymetrix PA1477_ccmC_at
DNASU PaCD00006681
Entrez 881087
GenBank AAG04866.1
INSDC AAG04866.1
NCBI Locus Tag PA1477
protein_id(GenBank) gb|AAG04866.1|AE004577_1|gnl|PseudoCAP|PA1477
TIGR NTL03PA01478
UniParc UPI00000C5398
UniProtKB Acc Q9I3N5
UniProtKB ID CCMC_PSEAE
UniRef100 UniRef100_Q9I3N5
UniRef50 UniRef50_Q9I3N5
UniRef90 UniRef90_Q9I3N5

Product

Feature Type CDS
Coding Frame 1
Product Name
heme exporter protein CcmC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 9.55
Kyte-Doolittle Hydrophobicity Value 0.704
Molecular Weight (kDa) 28.3
Isoelectric Point (pI) 9.78

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 253 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001392 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1477
Search term: ccmC

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM
Science 1995 Jul;269(5223):496-512
PubMed ID: 7542800
Molecular mechanisms of cytochrome c biogenesis: three distinct systems.
Kranz R, Lill R, Goldman B, Bonnard G, Merchant S
Mol. Microbiol. 1998 Jul;29(2):383-96
PubMed ID: 9720859