Pseudomonas aeruginosa PAO1, PA2158

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2158
Name
Replicon chromosome
Genomic location 2377480 - 2378727 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250848.1
GI 15597354
Affymetrix PA2158_at
Entrez 881293
GenBank AAG05546.1
INSDC AAG05546.1
NCBI Locus Tag PA2158
protein_id(GenBank) gb|AAG05546.1|AE004642_13|gnl|PseudoCAP|PA2158
TIGR NTL03PA02158
UniParc UPI00000C55DC
UniProtKB Acc Q9I1V7
UniProtKB ID Q9I1V7_PSEAE
UniRef100 UniRef100_W0YPB2
UniRef50 UniRef50_B2AIN0
UniRef90 UniRef90_A0A0A8RMM9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable alcohol dehydrogenase (Zn-dependent)
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -7.55
Kyte-Doolittle Hydrophobicity Value -0.074
Molecular Weight (kDa) 44.3
Isoelectric Point (pI) 5.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 544 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003315 (1429 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2158

Human Homologs

Ensembl 110, assembly GRCh38.p14
alcohol dehydrogenase 6 (class V) [Source:HGNC Symbol;Acc:HGNC:255]
E-value: 2.8e-16
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
alcohol dehydrogenase 6 (class V) [Source:HGNC Symbol;Acc:HGNC:255]
E-value: 2.8e-16
Percent Identity: 28.0
Ensembl 110, assembly GRCh38.p14
alcohol dehydrogenase 6 (class V) [Source:HGNC Symbol;Acc:HGNC:255]
E-value: 2.8e-16
Percent Identity: 28.0

References

Sequence of the gene for a NAD(P)-dependent formaldehyde dehydrogenase (class III alcohol dehydrogenase) from a marine methanotroph Methylobacter marinus A45.
Speer BS, Chistoserdova L, Lidstrom ME
FEMS Microbiol Lett 1994 Sep 1;121(3):349-55
PubMed ID: 7926692