Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3763
|
Name |
purL
|
Replicon | chromosome |
Genomic location | 4215544 - 4219440 (- strand) |
Transposon Mutants | 7 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_252452.1 |
GI | 15598958 |
Affymetrix | PA3763_purL_at |
Entrez | 879752 |
GenBank | AAG07150.1 |
INSDC | AAG07150.1 |
NCBI Locus Tag | PA3763 |
protein_id(GenBank) | gb|AAG07150.1|AE004795_2|gnl|PseudoCAP|PA3763 |
TIGR | NTL03PA03763 |
UniParc | UPI0000132A5B |
UniProtKB Acc | Q9HXN2 |
UniProtKB ID | PUR4_PSEAE |
UniRef100 | UniRef100_Q9HXN2 |
UniRef50 | UniRef50_P15254 |
UniRef90 | UniRef90_Q9HXN2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
phosphoribosylformylglycinamidine synthase
|
Synonyms |
formylglycinamide ribotide amidotransferase |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -47.15 |
Kyte-Doolittle Hydrophobicity Value | -0.165 |
Molecular Weight (kDa) | 140.6 |
Isoelectric Point (pI) | 4.81 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | Victors : 4233 |
Category | |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | |
Infection model | Rat agar bead model of chronic lung infection |
Reference | 14641575 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 621 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001918 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3763
Search term: purL
Search term: phosphoribosylformylglycinamidine synthase
|
Ensembl
110, assembly
GRCh38.p14
|
phosphoribosylformylglycinamidine synthase [Source:HGNC Symbol;Acc:HGNC:8863]
E-value:
9.8e-225
Percent Identity:
36.7
|
The organization of the purL gene encoding 5'-phosphoribosylformylglycinamide amidotransferase of Escherichia coli.
Sampei G, Mizobuchi K
J Biol Chem 1989 Dec 15;264(35):21230-8
PubMed ID: 2531746
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|