Pseudomonas fluorescens SBW25, PFLU1379 (acrB)

Gene Feature Overview

Strain	Pseudomonas fluorescens SBW25 GCF_000009225.2|latest
Locus Tag	PFLU1379
Name	acrB
Replicon	chromosome
Genomic location	1522656 - 1525817 (- strand)

Cross-References

RefSeq	YP_002871028.1
GI	229588909
Entrez	7817845
INSDC	CAY47633.1
UniParc	UPI00019D9C50
UniProtKB Acc	C3KBN3
UniProtKB ID	C3KBN3_PSEFS
UniRef100	UniRef100_C3KBN3
UniRef50	UniRef50_P24177
UniRef90	UniRef90_C3KBN3

Product

Feature Type	CDS
Coding Frame	1
Product Name	acriflavine resistance protein B
Synonyms
Evidence for Translation
Charge (pH 7)	-4.10
Kyte-Doolittle Hydrophobicity Value	0.323
Molecular Weight (kDa)	112.7
Isoelectric Point (pI)	6.17

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
adeF	AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879]	ARO:3000777	protein homolog model		Strict	751.1	41.6	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000417 (2093 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFLU1379 Search term: acrB Search term: acriflavine resistance protein B

Human Homologs

References