Pseudomonas aeruginosa UCBPP-PA14, PA14_45640 (fleN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_45640
Name
fleN
Replicon chromosome
Genomic location 4059416 - 4060258 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_791798.1
GI 116049399
Entrez 4380181
INSDC ABJ10635.1
NCBI Locus Tag PA14_45640
UniParc UPI00000D426B
UniProtKB Acc Q02JT8
UniProtKB ID Q02JT8_PSEAB
UniRef100 UniRef100_G3XD64
UniRef50 UniRef50_G3XD64
UniRef90 UniRef90_G3XD64

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar synthesis regulator FleN
Synonyms
Evidence for Translation
Charge (pH 7) 3.62
Kyte-Doolittle Hydrophobicity Value 0.196
Molecular Weight (kDa) 30.0
Isoelectric Point (pI) 8.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5J1J TRANSCRIPTION 03/29/16 Structure of FleN-AMPPNP complex Pseudomonas aeruginosa PAO1 1.55 X-RAY DIFFRACTION 100.0
7EJW TRANSCRIPTION 04/02/21 Crystal structure of FleN in complex with FleQ AAA+ doamain Pseudomonas aeruginosa PAO1 1.98 X-RAY DIFFRACTION 100.0
5JVF TRANSCRIPTION 05/11/16 Crystal Structure of Apo-FleN Pseudomonas aeruginosa PAO1 1.66 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 637 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001369 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_45640
Search term: fleN

Human Homologs

Ensembl 110, assembly GRCh38.p14
NUBP iron-sulfur cluster assembly factor 2, cytosolic [Source:HGNC Symbol;Acc:HGNC:8042]
E-value: 5.9e-10
Percent Identity: 26.6

References

No references are associated with this feature.