Pseudomonas aeruginosa UCBPP-PA14, PA14_52580 (lysC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
GCF_000014625.1|latest
Locus Tag
PA14_52580
Name
lysC
Replicon chromosome
Genomic location 4660763 - 4662001 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14

Cross-References

RefSeq YP_792372.1
GI 116048828
EC Number 2.7.2.4
Entrez 4383135
INSDC ABJ10064.1
NCBI Locus Tag PA14_52580
UniParc UPI0000125788
UniProtKB Acc Q02I64
UniProtKB ID Q02I64_PSEAB
UniRef100 UniRef100_O69077
UniRef50 UniRef50_A4VJB4
UniRef90 UniRef90_A4VJB4

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartate kinase
Synonyms
Evidence for Translation
Charge (pH 7) -11.08
Kyte-Doolittle Hydrophobicity Value 0.043
Molecular Weight (kDa) 44.4
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5YEI TRANSFERASE 09/17/17 Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase PSEUDOMONAS AERUGINOSA (STRAIN ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.301 X-RAY DIFFRACTION 100.0

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000015
mutant phenotype evidence
Host Organism Caenorhabditis elegans
Notes
Infection model C. elegans slow killing assay.
Reference 22911607

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 637 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000871 (547 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_52580
Search term: lysC
Search term: aspartate kinase

References

No references are associated with this feature.