Pseudomonas aeruginosa PA7, PSPA7_0296 (mdcE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_0296
Name
mdcE
Replicon chromosome
Genomic location 308796 - 309602 (+ strand)

Cross-References

RefSeq YP_001345692.1
GI 152988758
EC Number 4.1.-.-
Entrez 5354082
INSDC ABR85941.1
NCBI Locus Tag PSPA7_0296
UniParc UPI0000D73553
UniProtKB Acc A6UY07
UniProtKB ID A6UY07_PSEA7
UniRef100 UniRef100_A6UY07
UniRef50 UniRef50_W0V3F6
UniRef90 UniRef90_A6UY07

Product

Feature Type CDS
Coding Frame 1
Product Name
malonate decarboxylase subunit gamma
Synonyms
Evidence for Translation
Charge (pH 7) -0.07
Kyte-Doolittle Hydrophobicity Value 0.012
Molecular Weight (kDa) 28394.2
Isoelectric Point (pI) 6.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5VIP TRANSFERASE 04/17/17 Crystal structure of Pseudomonas malonate decarboxylase MdcD-MdcE hetero-dimer Pseudomonas aeruginosa 1.857 X-RAY DIFFRACTION 91.0
5VJ1 TRANSFERASE 04/18/17 Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with coenzyme A Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) 2.995 X-RAY DIFFRACTION 91.0
5VIT TRANSFERASE 04/17/17 Crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer in complex with malonate Pseudomonas aeruginosa; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) 2.203 X-RAY DIFFRACTION 91.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 57 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000211 (478 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_0296
Search term: mdcE

Human Homologs

References

No references are associated with this feature.