Pseudomonas aeruginosa PA7, PSPA7_4578 (cysM)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_4578
Name	cysM
Replicon	chromosome
Genomic location	4698140 - 4699039 (- strand)

Cross-References

RefSeq	YP_001349926.1
GI	152985911
EC Number	2.5.1.47
Entrez	5357721
INSDC	ABR83094.1
NCBI Locus Tag	PSPA7_4578
UniParc	UPI0000D724EB
UniProtKB Acc	A6VA41
UniProtKB ID	A6VA41_PSEA7
UniRef100	UniRef100_A6VA41
UniRef50	UniRef50_P16703
UniRef90	UniRef90_Q9I526

Product

Feature Type	CDS
Coding Frame	1
Product Name	cysteine synthase B
Synonyms
Evidence for Translation
Charge (pH 7)	-5.12
Kyte-Doolittle Hydrophobicity Value	-0.258
Molecular Weight (kDa)	32392.6
Isoelectric Point (pI)	5.23

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 633 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000898 (538 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_4578 Search term: cysM Search term: cysteine synthase B

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000344460 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] E-value: 1.9e-46 Percent Identity: 36.9
Ensembl 110, assembly GRCh38.p14	ENSP00000381231 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] E-value: 1.9e-46 Percent Identity: 36.9
Ensembl 110, assembly GRCh38.p14	ENSP00000381225 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] E-value: 1.9e-46 Percent Identity: 36.9
Ensembl 110, assembly GRCh38.p14	ENSP00000352643 cystathionine beta-synthase [Source:HGNC Symbol;Acc:HGNC:1550] E-value: 1.9e-46 Percent Identity: 36.9

References