Pseudomonas syringae pv. tomato DC3000, PSPTO_4220 (lepA)

Gene Feature Overview

Strain	Pseudomonas syringae pv. tomato DC3000 (Buell et al., 2003) GCF_000007805.1|latest
Locus Tag	PSPTO_4220
NCBI Old Locus Tag	PSPTO4220
Name	lepA Synonym: PSPTO4220
Replicon	chromosome
Genomic location	4752342 - 4754129 (- strand)

Cross-References

RefSeq	NP_793981.1
GI	28871362
Entrez	1185900
INSDC	AAO57676.1
NCBI Locus Tag	PSPTO_4220
NCBI Old Locus Tag	PSPTO4220
UniParc	UPI0000009233
UniProtKB Acc	Q87XF8
UniProtKB ID	LEPA_PSESM
UniRef100	UniRef100_Q87XF8
UniRef50	UniRef50_O67618
UniRef90	UniRef90_Q87XF8

Product

Feature Type	CDS
Coding Frame	1
Product Name	GTP-binding protein LepA
Synonyms
Evidence for Translation
Charge (pH 7)	-10.57
Kyte-Doolittle Hydrophobicity Value	-0.071
Molecular Weight (kDa)	65.9
Isoelectric Point (pI)	5.77

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000741 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPTO_4220 Search term: lepA Search term: GTP-binding protein LepA

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000281543 GTP binding elongation factor GUF1 [Source:HGNC Symbol;Acc:HGNC:25799] E-value: 1.6e-174 Percent Identity: 49.5

References