Pseudomonas protegens Pf-5, PFL_0022 (def_2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas protegens Pf-5
GCF_000012265.1|latest
Locus Tag
PFL_0022
Name
def_2
Replicon chromosome
Genomic location 23992 - 24498 (- strand)

Cross-References

RefSeq YP_257174.2
GI 161501956
EC Number 3.5.1.88
Entrez 3480622
INSDC AAY95440.2
NCBI Locus Tag PFL_0022
UniParc UPI000160BD55
UniProtKB Acc Q4KKQ9
UniProtKB ID Q4KKQ9_PSEF5
UniRef100 UniRef100_Q4KKQ9
UniRef50 UniRef50_Q5F5P6
UniRef90 UniRef90_Q4KKQ9

Product

Feature Type CDS
Coding Frame 1
Product Name
peptide deformylase
Synonyms
Evidence for Translation
Charge (pH 7) -7.13
Kyte-Doolittle Hydrophobicity Value -0.404
Molecular Weight (kDa) 19.3
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1IX1 HYDROLASE 06/07/02 Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin Pseudomonas aeruginosa 1.85 X-RAY DIFFRACTION 91.1
1LRY HYDROLASE 05/16/02 Crystal Structure of P. aeruginosa Peptide Deformylase Complexed with Antibiotic Actinonin Pseudomonas aeruginosa 2.6 X-RAY DIFFRACTION 91.0
1S17 HYDROLASE 01/05/04 Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors Pseudomonas aeruginosa 1.95 X-RAY DIFFRACTION 91.6
1N5N HYDROLASE 11/06/02 Crystal Structure of Peptide Deformylase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 91.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 587 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000019 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFL_0022
Search term: def_2

Human Homologs

References

No references are associated with this feature.