Pseudomonas aeruginosa PAO1, PA0686 (hxcR)

Annotation Updates

Date	Description	Acknowledgements
Jun 10, 2004	Annotation of gene described as probable type II secretion system protein (Class 3). New comment: Belongs to the GspE family (general secretory pathway). hxc gene cluster is under phosphate regulation. Hxc proteins are involved in alkaline phosphatase secretion. Added localization: Cytoplasmic. Added localization confidence: Class 2. New homology: 66% identical and 78% similar to GspE [Burkholderia pseudomallei]; 55% identical and 70% similar to XcpR [Pseudomonas aeruginosa]; 56% identical and 69% similar to XcpR [Pseudomonas alcaligenes]. New genomic context: Part of the hxcTXYZQRS operon. Ribosome binding site: GAGGCGGCG from -14 to -6. Kolaskar and Reddy rule for ATG: 22. New structure feature: Belongs to type II traffic warden ATPase family. New evidence references (PubMed IDs): 11985723; 9882649	Raymond C. Lo and Fiona S.L. Brinkman, Simon Fraser University, Canada (based on literature review);
May 8, 2015	New gene name: hxcR. New product name: HxcR. New product name confidence: Class 1.	Rome Voulhoux, CNRS, Marseille, France