Pseudomonas aeruginosa PAO1, PA0963 (aspS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016874 ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00459
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01042
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01042
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01336
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55261
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcription, RNA processing and degradation Other PAO1 genes in this class
Translation, post-translational modification, degradation Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 109 585 1.33E-102
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 475 491 4.7E-27
Gene3D G3DSA:3.30.1360.30 - IPR004115 GAD-like domain superfamily 274 423 0.0
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 2 106 7.43E-34
Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. IPR004524 Aspartate-tRNA ligase, type 1 2 585 33.861851
Pfam PF00152 tRNA synthetases class II (D, K and N) IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) 121 559 3.1E-108
NCBIfam TIGR00459 JCVI: aspartate--tRNA ligase IPR004524 Aspartate-tRNA ligase, type 1 1 583 0.0
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 1 107 2.5E-39
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 210 223 4.7E-27
PANTHER PTHR22594 ASPARTYL/LYSYL-TRNA SYNTHETASE - - 5 561 2.5E-118
Pfam PF01336 OB-fold nucleic acid binding domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 19 102 1.7E-16
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 193 205 4.7E-27
PRINTS PR01042 Aspartyl-tRNA synthetase signature IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb 519 533 4.7E-27
SUPERFAMILY SSF55261 GAD domain-like IPR004115 GAD-like domain superfamily 292 422 1.26E-44
CDD cd00777 AspRS_core IPR047090 Aspartate-tRNA ligase, type 1, core domain 141 560 0.0
CDD cd04317 EcAspRS_like_N IPR047089 Aspartate-tRNA ligase, type 1, anticodon recognition domain 3 137 1.60441E-77
Pfam PF02938 GAD domain IPR029351 GAD domain 310 409 1.4E-31
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 113 582 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.